Full instructions, dosage information and potential known side effects are all available in the leaflet that comes with the prescription product. If you require any advice or assistance with placing your order, please donâ€™t hesitate to contact our team.
How do I take/use this medicine?
Take Amitriptyline exactly as directed by your doctor. Do not take more or less than instructed by your doctor.
You may take Amitriptyline with or without food.
Amitriptyline must be taken regularly for it to work well. You may see the benefits of Amitriptyline only after 2-4 weeks. Do not be discouraged if you do not feel better soon after taking the medicine. Do not stop taking Amitriptyline unless instructed by your doctor. You may feel unwell if Amitriptyline is stopped suddenly.
What should I take note of while using/taking this medicine?
Alert your doctor if you have any of these conditions:
- other mood disorders such as schizophrenia
- a history of epilepsy (fits or seizures)\
- difficulty urinating
- glaucoma (increased pressure in the eyes)
- thyroid or adrenal gland disease
- Parkinsonâ€™s disease
Alert your doctor if you have recently undergone electroshock therapy (also known as electroconvulsive therapy or ECT).
If you need to go for elective surgery, let your doctor know you are being treated with Amitriptyline.
Amitriptyline increases the risk of suicidal thinking and behaviour in children, teenagers and adults younger than 24 years old. However, depression and some psychiatric disorders are themselves linked to an increased risk of suicide. It is important for you, or your family members, to monitor your condition while undergoing treatment.
Alert your doctor immediately if you notice a worsening of your depression, or if you have thoughts of harming yourself or others; or if you notice any other changes in your mood or behaviour.
When should I not use this medicine?
Alert your doctor if you have bipolar disorder, mania, heart disease or severe liver disease.
It is also important to let your doctor know if you are pregnant, planning to get pregnant, or breastfeeding.
Alert your doctor if you have taken other mood medicines known as monoamine oxidase inhibitors (MAOIs) in the last 14 days. Some examples of MAOIs include phenelzine, moclobemide and tranylcypromine.
Alert your doctor if you are being treated with a gastric reflux medicine known as cisapride.
Are there any restrictions on the type of food I can take?
Why do I need this medicine?
Amitriptyline is used to treat depression.
It can also be used to treat nerve-related pain and night-time bed-wetting.
Amitriptyline is also used to prevent migraine headaches.
What side effects could I experience?
Amitriptyline may make you drowsy or dizzy. If you feel drowsy or dizzy, do not drive or take part in any activity in which you need to be alert.
Amitriptyline may make you dizzy when you get up from a sitting or lying down position. To minimise this problem, stand up slowly.
You may also experience some problems with your eyesight, such as blurred vision. Always keep your doctor updated of any changes in your vision. Avoid driving and operating machinery if you are not able to see clearly.
Common side effects of Amitriptyline include:
- weakness or tiredness
- sensitivity to sunlight
- constipation or diarrhoea
- dry mouth
- nausea, vomiting
- loss of appetite
- weight gain or loss
- hair loss
- increased sweating
- changes in sex drive
Amitriptyline may have other side effects which are less common but may be more serious. Alert your doctor quickly if you notice any of the following:
- irregular or fast heart beat
- yellowing of the skin and white of the eyes (jaundice)
- breast development in males
- breast enlargement or milk production in females
- difficulty passing urine
- tingling and numbness in the hands and feet
- difficulty in controlling movements such as trembling or shaking of hands and feet, stiffness in the arms and legs muscles or shuffling of feet when walking
- severe sore throat and fever
- unusual bleeding or bruising
Alert your doctor if you experience any other side effects while being treated with Amitriptyline.
How should I store this medicine?
Store in a cool, dry place, protected from light, and away from the reach of children.
Medicines must not be used past the expiry date.
If you have been given Amitriptyline syrup, throw it away 6 months after opening.
Can I take/use this with other medicines?
Alert your doctor if you are taking any of these medicines:
- monoamine oxidase inhibitors (also used to treat depression) such as moclobemide, phenelzine, and tranylcypromine
- cisapride (a gastric reflux medicine)
- selegiline (a medicine for Parkinsonâ€™s disease)
- linezolid (an antibiotic)
- artemether and lumefantrine (malaria medicines)
You will also need to inform your doctor if you are taking any of these:
- other antidepressants, sedatives or anxiety medicines
- any other mood medicines
- epilepsy medicines
- blood pressure medicines such as gaunethidine, debrisoquine, betanidine and clonidine
- anticholinergics, commonly used to treat runny nose, allergies, travel sickness, such as chlorpheniramine, promethazine, hydroxyzine, and dimenhydrinate.
- cimetidine (a stomach medicine)
- heart medicines such as quinidine and flecainide
- disulfuram (a medicine used to treat alcoholism)
- painkillers such as tramadol, morphine or fentanyl
Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.