Full instructions, dosage information and potential known side effects are all available in the leaflet that comes with the prescription product. If you require any advice or assistance with placing your order, please donâ€™t hesitate to contact our team.
How do I take/use this medicine?
Use Estradiol exactly as directed by your doctor. Do not use more or less than instructed by your doctor.
Estradiol Transdermal is to be applied on the skin. The medication will be delivered into the body through the skin.
Estradiol Transdermal may be given in various forms, either as a patch or a gel.
If you have been given the PATCH:
1. Remove the patch from the pouch just before you use it.
2. Remove the backing and apply the patch to a clean, dry and intact area of the skin.
3. Firmly press the patch onto the skin with your palm.
4. Hold for about 10 seconds to ensure the patch sticks well to the skin.
5. You may apply the patch either on the torso, the abdomen or the buttocks. Do not apply Estradiol Transdermal on or near your breasts.
6. Try to avoid areas where the patch may be rubbed off by your clothes, such as the waistband area. Avoid areas which may be exposed to the sun.
7. Only ONE patch should be applied at any time, unless your doctor has specifically instructed you otherwise.
The patch will not fall out when you are bathing or swimming. However, if it does fall out, put the same patch back on and continue with the original schedule for that patch. If you really need to, you may use a new patch but continue to follow the original schedule.
Estradiol Transdermal must be kept on continuously until it is time to replace it with a new patch.
If you have been given the GEL:
1. Pump the prescribed dose from the bottle.
2. Apply to a clean, dry and intact area of skin, such as the arms, shoulders or inner thighs.
3. Spread the prescribed dose over the area of application. The area of application should be twice the area of the template provided.
4. The prescribed dose should be divided equally between each arm, shoulder or thigh.
5. Do not apply on or near the breasts or the vulval region.
6. After application, let the gel dry for 5 minutes before putting on your clothes.
7. You should apply the gel on your own. Avoid skin contact, especially with a male partner, for 1 hour after you have applied the gel.
8. Do not wash that particular area of skin or apply any other creams or lotions on that area for 1 hour after application.
Estradiol Transdermal must be used regularly for it to be effective. Continue using it even when you feel better. Do not stop using it unless instructed by your doctor.
What should I take note of while using/taking this medicine?
Inform your doctor if you have any of these conditions or any other illnesses:
- fits (epilepsy)
- kidney disease
- high blood pressure
- severe headache or migraine
- an ear problem called otosclerosis which causes ringing or buzzing in the ears and loss of hearing
- systemic lupus erythematosus (commonly known as lupus or SLE)
- high cholesterol
- thyroid problems
- low blood calcium
If you are going for any blood tests, inform your doctor that you are using Estradiol as it can interfere with certain laboratory tests.
Your doctor will also check your personal and family medical history and carry out a physical examination before starting you on Estradiol. He will also discuss with you the possible risk of breast cancer and blood clots while being treated with Estradiol.
Keep all appointments with your doctor so that he can monitor your response to Estradiol and any side effects that there may be.
If you are going for an operation, including minor operations and dental work, inform your doctor or dentist that you are being treated with Estradiol.
When should I not use this medicine?
Alert your doctor if you have any of these conditions:
- circulation problems or blood clots
- liver disease
- heart problems such as angina or a recent heart attack
- recent stroke
- cancer of the breast, womb or ovaries
- womb problems, such as thickening of the womb lining
- unexplained or unusual vaginal bleeding
- a blood condition called porphyria
Alert your doctor if you are pregnant or breastfeeding - Estradiol should not be used in these cases.
Why do I need this medicine?
Estradiol belongs to a group of female hormones known as estrogens.
Estradiol is used as hormone replacement therapy (HRT) in menopausal women.
It is used to treat menopausal symptoms such as hot flushes, vaginal dryness and itch. Estradiol is also used to prevent osteoporosis in menopausal women.
It is sometimes used in younger women when the ovaries fail to make enough estrogens.
What side effects could I experience?
Some common side effects of Estradiol include headache, nausea, stomach pain and discomfort, stomach wind, bloating or water retention, vaginal discharge or discomfort and breast tenderness.
Alert your doctor if any of these side effects are severe or refuse to go away.
Some side effects may be serious although they are not common. Alert your doctor quickly if you experience:
- swelling, pain or tenderness in the calf of your legs
- difficulty breathing or chest discomfort
- unexplained severe headache or migraine
- changes in your vision
- numbness of the arms or legs or over one side of your body
- breast lumps, dimples in the skin around the breast or changes in the nipple
How should I store this medicine?
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.
Can I take/use this with other medicines?
Alert your doctor and pharmacist if you are taking any of these medicines:
- antibiotics such as rifampicin or rifabutin
- epilepsy (fits) medicines such as phenobarbitone, phenytoin or carbamazepine
- antivirals such as ritonavir
- St John's wort (a herbal remedy)
Always inform your doctor or pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.