Full instructions, dosage information and potential known side effects are all available in the leaflet that comes with the prescription product. If you require any advice or assistance with placing your order, please donâ€™t hesitate to contact our team.
How do I take/use this medicine?
Take Duloxetine exactly as directed by your doctor. Do not take more or less than instructed by your doctor. Do not take Duloxetine for a longer period of time than instructed by your doctor.
You may need to take Duloxetine for some time before the full benefits can be felt. Continue to take it even when you feel better. Do not skip any doses. Do not stop taking Duloxetine unless advised by your doctor to do so. Do not stop taking Duloxetine suddenly as this may worsen your condition or cause side effects to appear. Your doctor will gradually reduce the dose before stopping it or changing it to another medicine.
You may take Duloxetine with or without food. Try to take it at the same time each day. Swallow the capsule whole. Do not chew or crush it.
What should I take note of while using/taking this medicine?
Alert your doctor immediately if you develop any of the following symptoms:
- thoughts of suicide
- unusual change in behaviour especially mood swings, agitation, irritability, aggressiveness
- worsening depression
Ask your family members to monitor you closely for any such signs, especially when you first start Duloxetine, or if your dose of Duloxetine has recently been changed.
Do not give Duloxetine to children or teenagers unless instructed by the doctor. If your child or teenager has been given Duloxetine, monitor him or her closely for signs of mood changes, suicidal thoughts, worsening depression, panic attacks, aggressiveness or violence, problems sleeping or other side effects. Alert the doctor immediately if you notice anything unusual.
If you have diabetes, monitor your blood sugar more closely.
If you are going for an operation, including minor surgery or dental work, inform your doctor or dentist that you are taking Duloxetine.
Duloxetine is not a painkiller. Do not take Duloxetine for any other purpose other than what your doctor has advised.
Keep all appointments with your doctor. Do not miss any appointments. Your doctor needs to monitor your condition and response to Duloxetine.
When should I not use this medicine?
Alert your doctor immediately if you are currently taking or have recently taken, within the last 2 weeks, a medicine called a MAO inhibitor. Examples of such medicines are isocarboxazid, phenelzine, selegiline and tranylcypromine. Duloxetine should not be taken within 2 weeks of stopping a MAO inhibitor, and a MAO inhibitor should not be started within 5 days of stopping Duloxetine.
Alert your doctor if you have liver or kidney disease, high blood pressure, epilepsy (seizures/ fits) or an eye disease called glaucoma. You must inform your doctor if you or your family have a history of any psychiatric problems, especially if you have bipolar disorder (also known as manic-depression).
Inform your doctor if you drink alcohol, especially if you drink frequently or in large amounts.
Alert your doctor if you are pregnant, especially if you are in the 3rd trimester of pregnancy. Inform your doctor if you are breastfeeding. Do not breastfeed while being treated with Duloxetine.
Are there any restrictions on the type of food I can take?
Why do I need this medicine?
Duloxetine is used to treat depression and anxiety.
It is also used to treat nerve pain in people who have diabetes.
Duloxetine has also been used to control the bladder in women who have urinary incontinence.
What side effects could I experience?
Duloxetine may cause dizziness or drowsiness. If you feel dizzy or drowsy, do not drive or take part in any activity in which you need to be alert. Duloxetine may also cause blurred vision. Do not drive or operate machinery until you are sure that your eyesight is not affected.
Duloxetine may also cause nausea, dry mouth, diarrhoea, constipation, tiredness, sleepiness, problems sleeping, headache, muscle cramps and weakness. These side effects are usually temporary and should go away as your body gets used to the medicine.
Less commonly, Duloxetine may cause other side effects that are more serious and require prompt medical attention. Alert your doctor quickly if you experience any of these symptoms:
- unusual tiredness or weakness
- dark urine that is the colour of tea
- yellowing of the eyes or skin
- pain near the stomach area
- nausea or vomiting that gets worse or does not go away
How should I store this medicine?
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.
Can I take/use this with other medicines?
Do not take Duloxetine together with thioridazine or MAO inhibitors such as isocarboxazid, phenelzine, selegiline and tranylcypromine.
Alert your doctor if you are taking any of these medicines:
- antidepressants such as amitriptyline, desipramine, imipramine, nortriptyline, paroxetine, fluvoxamine
- any psychiatric medicines, especially thioridazine
- heart medicines such as flecainide, propafenone
- migraine medicines such as sumatriptan, zolmitriptan and related medicines
- painkillers such as tramadol and pethidine
- herbal medicines such as valerian root, St John's wort
Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.